Aaron Kampman was highly recruited out of high school, and he chose to play for the University of Iowa and Hall of Fame coach Hayden Fry. Kampman played nine games as a true freshman in 1998, recording 49 tackles. After the season, Coach Fry retired, and Kampman played the rest of his career for Kirk Ferentz.
As a sophomore, Kampman started all 11 games for Iowa at linebacker, and he finished second on the team with 103 tackles. He had five games with ten or more tackles in 1999 and was academic All-Big Ten.
Prior to his junior season, Kampman switched positions from linebacker to defensive end. In 2000, he started all 12 games for Iowa at defensive end, but Iowa was struggling on the field. The Hawkeyes snapped a school-record 13 game losing streak when they defeated Michigan State, 21-16. Kampman was the Big Ten Defensive Player of the Week that week, recording 16 tackles, a blocked field goal, and the first interception of his career. He had 94 tackles his junior season, and he was named honorable mention All-Big Ten. He was also a second team academic All-American.
As a senior in 2001, Aaron Kampman started all 12 games for Iowa at defensive end. He had 96 tackles in 2001 and led the team with nine sacks. Iowa, which had only won seven games in Kampman's first three years combined, rebounded in 2001. The Hawkeyes faced Minnesota, needing just one more win to clinch their first winning record and first bowl bid since 1997. Kampman responded with possibly the best game of his college career, making 15 tackles and three sacks and leading Iowa to a 42-24 victory. He was named Big Ten Defensive Player of the Week for the second time in his career. He also had four tackles in his final game, Iowa's 19-16 win in the 2001 Alamo Bowl.
Kampman won the Hayden Fry "Extra Heartbeat" award and Iowa's Scholastic Achievement award. He was named first team All-Big Ten and co-captain of the 2001 Hawkeyes. He finished his career with 342 tackles, the seventh best total in Iowa history. Kampman also named a first team academic All-American in 2001