Man, do we outrank them in the stat department...
Simply said, if our defense shows up like it did last week, the 49ers won't have a chance. Their QB position is too unstable, apart from Staley they don't have any great blockers up front and their WRs are good, but not great. Not now, at least. Great potential there, though. Frank Gore is pretty scary, but if we can contain him like we did with AP etc. we should be ok.
On the other side, they're coached by Singletary. The magic appears to have worked out a little by now, but the man gets his players ready. The most fiery coach I know. He pushes them to their limits. We'll see how that'll work out. If they can figure something out to get some pressure, this might be a long day.
That said, besides Haralson, who is a decent pass rusher, they don't have anyone to get to us. Their ILB tandem is pretty scary with Spikes and Willis, but they're mainly run stoppers. Willias can cover, as well. Their CBs, combined with their average pass rush, should make for a good day for our offense.
Then again, it looked like that against Tampa, as well.
If we go into this game the exact same way we went into last weeks, we'll win. We'll just have to execute. Especially if you want to run screens against Willis. Someone has to pick that guy up, because he's going to see through it in no time.