A rule in the National Football League which allows teams to designate players as "Physically Unable to Perform" or "PUP". Once they are designated as such, they are prohibited from practicing with the team. They can, however, rehabilitate and participate in team meetings. If a player begins training camp on the PUP list, they can be moved to the active roster at any time, even after one practice. A player is not allowed to be placed on the PUP list if they start training camp on the active roster.
A player who begins the season on the PUP list must sit out his team's first six games. After that point, the player is allowed to practice with the team through Week 10 of the NFL season, and can be activated any time within that window. If the player is not activated by Week 10, he must stop practicing and is unavailable to be moved to the active roster for the remainder of the season.